You will always find strange IPs trying to connect to strange ports if you check your firewall logs. People have scripts constantly scanning the web for open ports on venerable computers.
Your best bet would be to block those IP addresses from passing through your firewall. Your even safer route would be to block all incoming ports and then poke holes in your firewall for specific programs that need to use certain ports. You will still see the IPs in your logs but you wont have to worry about them breaching your firewall.
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